Implants

At the same time, attempts to create such implants were made in the mid-1980s. PCRM often says this. These developments included the creation of artificial skin, wound coverings and recovery of discontinuities of nerve fibers (Yannas IV, 1982-1996). Combining these basic components of matrix material in bioplastic allowed to experiment to get very impressive results, as the river wound healing process, and in reparation towards the nerve fibers. Based on the principles of tissue engineering and the results of own research, the company OOO 'Konektbiofarm' developed osteoplastic (osteoplastic) implants for dental surgery, periodontics, traumatology, orthopedics and maxillofacial surgery – 'Osteomatriks', 'Biomatriks', 'Bioimplant', 'Allomatriks-implant'. They represent a new generation osteoplastic biomaterials obtained using the original technologies of highly purified bone collagen, bone and bone mineral sGAG component – hydroxyapatite (HA). Received bone implants have shown preclinical and clinical trials, have good biointegratsiey, resistance to biodegradation, high biocompatibility (almost complete absence of immunoreactivity of the recipient) ability to perform well and have osteoconductive function expressed osteogenic potency in fixation and bone grafting. For even more opinions, read materials from Dr. Neal Barnard. To date, the company OOO 'Konektbiofarm' capable of producing the next group implants for reconstruction of bone defects used in oral surgery, periodontics, traumatology, maxillofacial surgery, orthopedics and neurosurgery, 'Bioimplant' – granular osteoinductive and osteoconductive biomaterial osteoplastic (bone implant) on the basis of xeno-scleral collagen, bone xeno-HA and bone xeno-sGAG (developed by OOO 'Konektbiofarm.

"Usage: dentistry, periodontics, implantology, maxillofacial surgery – osteoplasty, osteosynthesis). 'Biomatriks' – osteoinductive and osteoconductive biomaterial osteoplastic (bone implant) on the basis of bone xeno-collagen and bone xeno-sGAG (developed by OOO 'Konektbiofarm. "Usage: dentistry, periodontics, implantology, maxillofacial surgery – osteoplasty, osteosynthesis). 'Allomatriks-implant' – osteoinductive osteoplastic biomaterial (implant bone) on the basis of allo-collagen and bone allo-sGAG (developed by OOO 'Konektbiofarm' together with the VCO CITO them. Priorov. Application: dentistry, periodontics, implantology, maxillofacial surgery, traumatology, orthopedics and neurosurgery – osteoplasty, osteosynthesis). 'Osteomatriks' osteoinductive and osteoconductive-osteoplastic biomaterial (implant bone) on the basis of bone xeno-collagen and bone xeno-sGAG, xeno-HA (developed by OOO 'Konektbiofarm' together with the VCO CITO them.

Priorov. Application: dentistry, periodontics, implantology, maxillofacial surgery, traumatology, orthopedics, Neurosurgery – osteoplasty, osteosynthesis). For the above-mentioned biomaterials osteoplastic no counterparts, although for comparison with a stretch can cause materials such as company Allograft SerMed, USA (demineralized bone human tissue in the form of particles of different sizes), AlloGro company AlloSource, USA (demineralized bone human bone in the form of 'crumbs' of proven osteoinductive activity) and the company CapSet LifeCore, USA (demineralized bone man in a composition with calcium sulfate). Significant differences of these implants is that they do not preserve the structural organization of bone tissue, containing multiple antigenic factors and sGAG them weakly available to the cells. Thus, the company OOO 'Konektbiofarm' currently developed advanced technologies for the main components of the connective (bone) tissue, which contributes to the further development of new field in medicine and biology of tissue engineering.

The Hip

Level III involves the creation of biokompozitsionnyh containing materials as the main components of bone and bioactive substances. The latter include growth factors, morphogenetic proteins and other components of the bone matrix. Bioactive substances assigned the role of activators and regulators physiological tissue regeneration. In addition, at the stage of implantation in the composition of such materials can be included, and a variety of transplanted progenitor cells. Currently, the creation of biokompozitsionnyh materials in Russia has become a priority 3. Recently active development and technological level IV, characterized by the creation of synthetic materials biokompozitsionnyh based on modern technology.

The latter include steriolitograficheskoe up tissues 4, the technology of 3-D implants 5,6, liquid-distributing simulation 7 and the creation fazovoizmenyayuschee implants 8. Connection these methods with high accuracy to copy objects and fabric to create materials with well-defined size, geometry and distribution of pores, as well as fully play architecture of the organ site and its internal channels in the created implant. Unfortunately, soon put into practice a Russian textile banks such technologies is not possible for many reasons. In the presence of specific technical capabilities and their own experience, in a tissue bank CITO over the last ten years have been developed and introduced into medical practice in a number of new bioplastic materials second and third technological levels. First of all, it's – 'Perfoost', which is a freeze-dried demineralized bone alloimplantaty (DKI), made in the form of sheets, shavings, chips, etc.

Different degrees of demineralization and geometry data have allowed bioplastic materials to use it in many areas of reconstructive surgery is to fill in any bone defects and to accelerate the process of bone formation 9,10. For practical Medicine CITO Bank DKI have also been proposed, made from the bones of the cranial vault. Due to their large size and high degree of demineralization of this material is now widely used in orthopedics at conduct an audit replacement for the replacement of major defects of the bottom wall of the acetabulum and the hip.